Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14225884 | 0.84 | TRPA1 (0.46) | TRPA1SIGMAR1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL8072287 | 0.84 | SIGMAR1 (0.58) | TRPA1SIGMAR1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL8983689 | 0.82 | TAAR1 (0.56) | TRPA1SIGMAR1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL14799062 | 0.82 | TAAR1 (0.56) | TRPA1SIGMAR1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL535702 | 0.82 | TAAR1 (0.56) | TRPA1SIGMAR1TAAR1SLC6A2SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL5082413 | 0.80 | TAAR1 (0.54) | TRPA1SIGMAR1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL7394097 | 0.80 | TAAR1 (0.54) | TRPA1SIGMAR1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL11880796 | 0.80 | TAAR1 (0.55) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3672929 | 0.79 | TRPA1 (0.67) | TRPA1TAAR1SLC6A3ADRA2BHTR2A | |
| SCHEMBL4785594 | 0.79 | SIGMAR1 (0.64) | TRPA1SIGMAR1TAAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967229-B2 | Carbon-carbon initiators for use in golf balls | ACUSHNET COMPANY (US) | 2005-11-22 | — | — | US | claimed |
| US-20050009992-A1 | Carbon-carbon initiators for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | claimed |
| CN-1193993-A | Cleaning composition containing an aliphatic hydrocarbon compound with at least two aromatic substituents | RHODIA CHEMIC S A (FR) | 1998-09-23 | — | — | CN | claimed |
| US-9056227-B2 | Golf ball comprising a core having a shallow hardness gradient | ACUSHNET COMPANY (US) | 2015-06-16 | — | — | US | disclosed |
| US-8968117-B2 | Dual-core comprising zero gradient center and positive gradient outer core layer | ACUSHNET COMPANY (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130109504-A1 | DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER | ACUSHNET COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109506-A1 | GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT | ACUSHNET COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130012432-A1 | Peptides for Treatment of Obesity | NOVO NORDISK A/S (DK) | 2013-01-10 | — | — | US | disclosed |
| EP-2539364-A1 | PEPTIDES FOR TREATMENT OF OBESITY | Novo Nordisk A/S (DK) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011104378-A1 | PEPTIDES FOR TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011104379-A1 | PEPTIDES FOR TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2011-09-01 | — | — | WO | disclosed |
| WO-2008057645-A1 | PREPARATION OF HIGH ASSAY DECABROMODIPHENYLALKANE | ALBEMARLE CORPORATION (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20080108855-A1 | PREPARATION OF HIGH ASSAY DECABROMODIPHENYLALKANE | ALBEMARLE CORPORATION (US) | 2008-05-08 | — | — | US | disclosed |
| US-6967229-B2 | Carbon-carbon initiators for use in golf balls | ACUSHNET COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-20050009992-A1 | Carbon-carbon initiators for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | disclosed |
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| CN-1193993-A | Cleaning composition containing an aliphatic hydrocarbon compound with at least two aromatic substituents | RHODIA CHEMIC S A (FR) | 1998-09-23 | — | — | CN | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012432-A1 | Peptides for Treatment of Obesity | MC4R, GIPR, MC3R | TRPA1 1235/4885SIGMAR1 1168/4885TAAR1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.