SCHEMBL23698264

SCHEMBL23698264

[O]C(=O)c1ccc2ccc3ccccc3c2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
MAPT P10636 2/20 0.56
HPGD P15428 2/20 0.56
CASP3 P42574 1/20 0.55
GFER P55789 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
HSD17B10 Q99714 4/20 0.54
HIF1A Q16665 2/20 0.54
CYP1B1 Q16678 2/20 0.54
CYP1A2 P05177 4/20 0.50
CYP2D6 P10635 3/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP2A6 P11509 1/20 0.50
TP53 P04637 1/20 0.50
RAD52 P43351 1/20 0.50
GRIN2D O15399 1/20 0.47
GRIN2A Q12879 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21817642 0.90 ALDH1A1 (0.70) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL2469905 0.83 GRIN2D (0.66) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL50671 0.82 ALDH1A1 (0.82) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL11148876 0.82 ALDH1A1 (0.55) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL2887371 0.82 ALDH1A1 (0.55) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL1004717 0.82 ALDH1A1 (0.55) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL30301801 0.82 ALDH1A1 (0.82) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL196520 0.80 CES2 (0.71) ALDH1A1MAPTHPGDHSD17B10CYP1B1
SCHEMBL9625019 0.80 NPC1 (0.58) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL31742339 0.80 GRIN2D (0.67) ALDH1A1MAPTHPGDCASP3GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813979-A Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2023-09-29 CN disclosed
CN-112839988-B Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2023-06-06 CN disclosed
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-12-23 US disclosed
EP-3858909-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-08-04 EP disclosed
CN-112839988-A Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2021-05-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF NOC2L, RIF1, NAP1L1 ALDH1A1 2699/4885MAPT 1265/4885HPGD 3069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.