Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23698898 | 0.92 | ALDH1A1 (0.50) | HPGDESRRGKDM4ETMEM97SIGMAR1 | |
| SCHEMBL24100547 | 0.83 | HPGD (0.66) | HPGDKDM4EGLAL3MBTL1MAPK1 | |
| SCHEMBL7967927 | 0.82 | NPC1 (0.50) | HPGDKDM4EL3MBTL1MAPK1MEN1 | |
| SCHEMBL14316370 | 0.81 | ESRRG (0.59) | HPGDESRRGKDM4EMAPK1MEN1 | |
| SCHEMBL12124297 | 0.81 | MEN1 (0.56) | HPGDKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL489064 | 0.79 | ALDH1A1 (0.45) | HPGDKDM4EGLAALOX15HTT | |
| SCHEMBL20542375 | 0.79 | GAA (0.51) | ESRRGKDM4ETMEM97SIGMAR1KMT2A | |
| Acetic Acid SCHEMBL6453507 | 0.79 | KDM4E (0.50) | HPGDKDM4EL3MBTL1MAPK1MEN1 | |
| SCHEMBL27288206 | 0.78 | HPGD (0.46) | HPGDESRRGKDM4EL3MBTL1MAPK1 | |
| SCHEMBL30760510 | 0.76 | KMT2A (0.68) | HPGDMAPK1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12012419-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-06-18 | — | — | US | disclosed |
| CN-112752760-B | Heterocyclic compounds | 武田药品工业株式会社 | 2024-01-19 | — | — | CN | disclosed |
| US-20210347786-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-11-11 | — | — | US | disclosed |
| EP-3858838-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347786-A1 | HETEROCYCLIC COMPOUND | SLC10A2, ALPI, SLC10A1 | HPGD 159/4885ESRRG 4856/4885KDM4E 2171/4885 |
| US-12012419-B2 | Heterocyclic compound | SLC10A2, ALPI, SLC10A1 | HPGD 159/4885ESRRG 4856/4885KDM4E 2171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.