Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | EEF2K | O00418 | 2/20 | 0.45 |
| ▸ | EEF2 | P13639 | 2/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5304277 | 0.98 | PON1 (0.56) | PON1MEN1KMT2AEEF2KEEF2 | |
| Bromide SCHEMBL15819609 | 0.97 | PON1 (0.55) | PON1MEN1KMT2AEEF2KEEF2 | |
| Hydrochloric Acid SCHEMBL10882014 | 0.94 | PON1 (0.53) | PON1MEN1KMT2AEEF2KEEF2 | |
| Hydrochloric Acid SCHEMBL23698397 | 0.94 | PON1 (0.53) | PON1MEN1KMT2AEEF2KEEF2 | |
| Hydrochloric Acid SCHEMBL1879983 | 0.94 | PON1 (0.53) | PON1MEN1KMT2AEEF2KEEF2 | |
| SCHEMBL5048639 | 0.94 | PON1 (0.52) | PON1MEN1KMT2AEEF2KEEF2 | |
| SCHEMBL28223513 | 0.93 | PON1 (0.52) | PON1MEN1KMT2AEEF2KEEF2 | |
| SCHEMBL5304014 | 0.93 | MEN1 (0.53) | PON1MEN1KMT2AEEF2KEEF2 | |
| SCHEMBL5284658 | 0.93 | MEN1 (0.53) | PON1MEN1KMT2AEEF2KEEF2 | |
| SCHEMBL5295976 | 0.93 | MEN1 (0.53) | PON1MEN1KMT2AEEF2KEEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2025-05-06 | — | — | US | disclosed |
| CN-118290346-A | Method for producing amide compound, and amide compound | 广荣化学株式会社 | 2024-07-05 | — | — | CN | disclosed |
| CN-112703184-B | Method for producing amide compound, and amide compound | 广荣化学株式会社 | 2024-06-11 | — | — | CN | disclosed |
| US-20220048864-A1 | METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2022-02-17 | — | — | US | disclosed |
| EP-3858817-A1 | METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND | Koei Chemical Company, Limited (JP) | 2021-08-04 | — | — | EP | disclosed |
| CN-112703184-A | Process for producing amide compound, and amide compound | 广荣化学株式会社 | 2021-04-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | NAAA, NIT2, PAM | PON1 3751/4885MEN1 55/4885KMT2A 4207/4885 |
| US-20220048864-A1 | METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND | NAAA, NIT2, PAM | PON1 3751/4885MEN1 55/4885KMT2A 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.