SCHEMBL2369922

SCHEMBL2369922

CCCCCCCCN(CCCCCCCC)c1ccc(C(=O)C(=O)c2ccc(N(CCCCCCCC)CCCCCCCC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.53
ERBB2 P04626 2/20 0.53
CNR2 P34972 6/20 0.51
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
HDAC11 Q96DB2 1/20 0.44
PTGES O14684 2/20 0.43
ALOX5 P09917 2/20 0.43
NPC1 O15118 1/20 0.43
JAK2 O60674 1/20 0.43
RAB9A P51151 1/20 0.43
PAX8 Q06710 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2370361 0.94 CES2 (0.55) EGFRERBB2CNR2CES2CES1
SCHEMBL1963626 0.89 EGFR (0.53) EGFRERBB2CNR2HDAC11PTGES
SCHEMBL29138334 0.89 EGFR (0.53) EGFRERBB2CNR2HDAC11PTGES
SCHEMBL29138335 0.89 EGFR (0.53) EGFRERBB2CNR2HDAC11PTGES
SCHEMBL29138333 0.89 EGFR (0.53) EGFRERBB2CNR2HDAC11PTGES
SCHEMBL29138331 0.89 EGFR (0.53) EGFRERBB2CNR2HDAC11PTGES
SCHEMBL29138374 0.89 EGFR (0.53) EGFRERBB2CNR2HDAC11PTGES
SCHEMBL11539577 0.88 PTGES (0.54) EGFRERBB2CNR2PTGESALOX5
SCHEMBL472312 0.88 PTGES (0.54) EGFRERBB2CNR2PTGESALOX5
SCHEMBL3786342 0.88 PTGES (0.54) EGFRERBB2CNR2PTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133320-B2 Polyolefin composition for medium/high/extra high voltage cables comprising benzil-type voltage stabiliser BOREALIS AG (AT) 2015-09-15 US disclosed
US-9133320-B2 Polyolefin composition for medium/high/extra high voltage cables comprising benzil-type voltage stabiliser BOREALIS AG (AT) 2015-09-15 US disclosed
US-9133320-B2 Polyolefin composition for medium/high/extra high voltage cables comprising benzil-type voltage stabiliser BOREALIS AG (AT) 2015-09-15 US disclosed
EP-2545114-B1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZIL-TYPE VOLTAGE STABILISER BOREALIS AG (AT) 2013-08-21 EP disclosed
EP-2545114-B1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZIL-TYPE VOLTAGE STABILISER BOREALIS AG (AT) 2013-08-21 EP disclosed
US-20130025910-A1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZIL-TYPE VOLTAGE STABILISER BOREALIS AG (AT) 2013-01-31 US disclosed
US-20130025910-A1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZIL-TYPE VOLTAGE STABILISER BOREALIS AG (AT) 2013-01-31 US disclosed
US-20130025910-A1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZIL-TYPE VOLTAGE STABILISER BOREALIS AG (AT) 2013-01-31 US disclosed
EP-2545114-A1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZIL-TYPE VOLTAGE STABILISER Borealis AG (AT) 2013-01-16 EP disclosed
WO-2011110280-A1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZIL-TYPE VOLTAGE STABILISER BOREALIS AG (AT) 2011-09-15 WO disclosed
WO-2011110280-A1 POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZIL-TYPE VOLTAGE STABILISER BOREALIS AG (AT) 2011-09-15 WO disclosed