Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 8/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134696 | 1.00 | PTGES (0.54) | PTGESALOX5TP53TSHRRARB | |
| SCHEMBL472312 | 1.00 | PTGES (0.54) | PTGESALOX5TP53TSHRRARB | |
| SCHEMBL11539577 | 1.00 | PTGES (0.54) | PTGESALOX5TP53TSHRRARB | |
| SCHEMBL472292 | 0.98 | EGFR (0.53) | PTGESALOX5TP53TSHRRARB | |
| SCHEMBL472266 | 0.93 | EGFR (0.58) | ALOX5TP53TSHRRARBPLA2G4B | |
| SCHEMBL11373304 | 0.91 | EGFR (0.56) | PTGESALOX5TP53TSHRRARB | |
| SCHEMBL2369922 | 0.88 | EGFR (0.53) | PTGESALOX5EGFRERBB2CNR2 | |
| SCHEMBL1963626 | 0.88 | EGFR (0.53) | PTGESALOX5ALDH1A1MAPTEGFR | |
| SCHEMBL29138331 | 0.88 | EGFR (0.53) | PTGESALOX5ALDH1A1MAPTEGFR | |
| SCHEMBL29138333 | 0.88 | EGFR (0.53) | PTGESALOX5ALDH1A1MAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100322881-A1 | UVB FILTER BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100322881-A1 | UVB FILTER BASED ON ASCORBIC ACID DERIVATIVES | C1R, VDR, CYP2R1 | PTGES 4221/4885ALOX5 1503/4885TP53 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.