Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330941 | 0.82 | MEN1 (0.56) | OPRM1OPRL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23699396 | 0.78 | SMN1; SMN2 (0.60) | TMEM97SIGMAR1SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7559118 | 0.73 | OPRM1 (0.53) | OPRM1OPRL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23719083 | 0.73 | OPRL1 (0.41) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL23699334 | 0.72 | OPRL1 (0.41) | OPRM1OPRL1OPRK1 | |
| SCHEMBL324086 | 0.71 | TMEM97 (0.64) | TMEM97SIGMAR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23718993 | 0.70 | CCR5 (0.54) | OPRM1OPRL1OPRK1 | |
| SCHEMBL10123161 | 0.70 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL23719010 | 0.69 | KMT2A (0.48) | OPRM1OPRL1OPRK1 | |
| SCHEMBL23719120 | 0.69 | KMT2A (0.48) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |