SCHEMBL237003

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15452994	0.88	SERPINE1 (0.43)	SERPINE1MAPTTDP1LMNAHTT
	SCHEMBL242340	0.88	SERPINE1 (0.43)	SERPINE1MAPTTDP1LMNAHTT
	SCHEMBL241269	0.86	ALDH1A1 (0.37)	MAPTLMNAHTTL3MBTL1ALDH1A1
	SCHEMBL240260	0.86	ALDH1A1 (0.37)	MAPTLMNAHTTL3MBTL1ALDH1A1
	SCHEMBL238468	0.84	ALDH1A1 (0.39)	MAPTLMNAHTTL3MBTL1ALDH1A1
	SCHEMBL240305	0.84	ALDH1A1 (0.39)	MAPTLMNAHTTL3MBTL1ALDH1A1
	SCHEMBL240606	0.83	FFAR2 (0.38)	SERPINE1MAPTTDP1LMNAHTT
	SCHEMBL239304	0.82	MAPT (0.37)	MAPTTDP1LMNAHTTALDH1A1
	SCHEMBL240997	0.82	KMT2A (0.38)	MAPTLMNAL3MBTL1ALDH1A1MEN1
	SCHEMBL240827	0.82	FFAR4 (0.33)	MAPTTDP1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.