SCHEMBL23700583

SCHEMBL23700583

C[SiH](C)c1ccc(-c2ccc([Si](C)(C)c3ccc(-c4ccc([SiH](C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.41
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11416836 0.93 HPGD (0.46) HPGDESR1ESR2NR1H2NR1H3
SCHEMBL2579397 0.82 ALDH1A1 (0.32) ESR1ESR2
SCHEMBL3409938 0.77 NR1H2 (0.38) HPGDNR1H2NR1H3
SCHEMBL19785202 0.76 SCN5A (0.31)
SCHEMBL29242327 0.73 NR1I2 (0.35) HPGDESR1
SCHEMBL29273132 0.73
SCHEMBL21722327 0.73 ESR1 (0.56) ESR1ESR2
SCHEMBL18560096 0.73
SCHEMBL2438805 0.72
SCHEMBL148576 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497511-B2 Crosslinkable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2025-12-16 US disclosed
US-12187854-B2 Crosslinkable organosiloxane compositions WACKER CHEMIE AG (DE) 2025-01-07 US disclosed
US-12110393-B2 Crosslinkable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2024-10-08 US disclosed
CN-112996841-B Crosslinkable organosiloxane compositions 瓦克化学股份公司 2022-12-27 CN disclosed
CN-111936582-B Crosslinkable organosiloxane compositions 瓦克化学股份公司 2022-06-17 CN disclosed
CN-111936556-B Crosslinkable organosiloxane compositions 瓦克化学股份公司 2022-05-03 CN disclosed
EP-3837317-B1 CROSSLINKABLE ORGANOSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2022-04-20 EP disclosed
US-20210347952-A1 CROSSLINKABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2021-11-11 US disclosed
US-20210309856-A1 CROSSLINKABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2021-10-07 US disclosed
US-20210238366-A1 CROSSLINKABLE ORGANOSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2021-08-05 US disclosed
CN-112996841-A Crosslinkable organosiloxane compositions 瓦克化学股份公司 2021-06-18 CN disclosed
CN-111936556-A Crosslinkable organosiloxane compositions 瓦克化学股份公司 2020-11-13 CN disclosed
CN-111936582-A Crosslinkable organosiloxane compositions 瓦克化学股份公司 2020-11-13 CN disclosed