SCHEMBL23701142

SCHEMBL23701142

CC(O)[SiH](C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HBB P68871 1/20 0.39
LMNA P02545 3/20 0.38
KDM4E B2RXH2 3/20 0.38
ADRA2C P18825 2/20 0.38
ADRA2A P08913 1/20 0.38
HIF1A Q16665 1/20 0.38
CACNA2D1 P54289 1/20 0.36
CACNB2 Q08289 1/20 0.36
CACNA1C Q13936 1/20 0.36
TSHR P16473 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2D6 P10635 2/20 0.35
CHRM2 P08172 1/20 0.35
ADRA1A P35348 1/20 0.35
RGS12 O14924 1/20 0.35
GLA P06280 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19890844 1.00 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AHBBLMNA
SCHEMBL8992273 0.79 TDP1 (0.35) ALDH1A1LMNAKDM4EADRA2CADRA2A
SCHEMBL27627719 0.72 F2 (0.32) LMNATSHRALOX12
SCHEMBL5613374 0.72 F2 (0.32) LMNATSHRALOX12HTR2A
SCHEMBL27955651 0.72 TSHR (0.38) LMNATSHRALOX12
SCHEMBL19890843 0.70 LMNA (0.43) ALDH1A1LMNAKDM4ETSHRCYP2D6
Hydrochloric Acid SCHEMBL11803910 0.69 TSHR (0.37) ALDH1A1LMNAKDM4ETSHRGLA
SCHEMBL7785328 0.68
SCHEMBL5872426 0.68 CA4 (0.35) ALDH1A1KMT2ALMNAKDM4EHIF1A
SCHEMBL571308 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed