SCHEMBL23701255

SCHEMBL23701255

CC(F)C(O[SiH3])(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
ALOX15 P16050 1/20 0.34
CYP2D6 P10635 2/20 0.33
CYP1A2 P05177 1/20 0.33
KCNN4 O15554 4/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703675 0.83 CYP2D6 (0.39) MAPK1ALDH1A1TSHRALOX15CYP2D6
SCHEMBL5024571 0.79 CYP1A2 (0.37) MAPK1ALDH1A1ALOX15CYP2D6CYP1A2
SCHEMBL23701218 0.79 MAPK1 (0.37) MAPK1ALDH1A1TSHRALOX15CYP2D6
SCHEMBL703112 0.78 MAPK1 (0.35) MAPK1ALDH1A1ALOX15CYP2D6CYP1A2
SCHEMBL1314414 0.76 KIF11 (0.39) MAPK1ALDH1A1ALOX15CYP2D6KCNN4
SCHEMBL27614171 0.76 CYP2D6 (0.35) MAPK1ALDH1A1TSHRALOX15CYP2D6
SCHEMBL3481511 0.73 CYP2D6 (0.35) MAPK1ALDH1A1CYP2D6KCNN4CYP2C19
SCHEMBL28058949 0.72 MAPK1 (0.33) MAPK1ALDH1A1TSHRALOX15KCNN4
SCHEMBL29546596 0.72 MAPK1 (0.39) MAPK1ALDH1A1ALOX15KCNN4TAAR1
SCHEMBL3482030 0.72 KEAP1 (0.37) MAPK1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed