Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444220 | 0.82 | TSHR (0.43) | CA2TSHRCA1TP53ALDH1A1 | |
| SCHEMBL23701057 | 0.82 | CA2 (0.43) | CA2TSHRCA1TP53ALDH1A1 | |
| SCHEMBL18043733 | 0.82 | TSHR (0.43) | CA2TSHRCA1TP53ALDH1A1 | |
| SCHEMBL10664532 | 0.80 | ALDH1A1 (0.38) | CA2TSHRCA1TP53ALDH1A1 | |
| SCHEMBL2201668 | 0.79 | CA2 (0.44) | CA2TSHRCA1TP53ALDH1A1 | |
| SCHEMBL31542131 | 0.79 | CA2 (0.44) | CA2TSHRCA1TP53ALDH1A1 | |
| SCHEMBL19809443 | 0.79 | CA2 (0.44) | CA2TSHRCA1TP53ALDH1A1 | |
| SCHEMBL29444240 | 0.79 | CA2 (0.44) | CA2TSHRCA1TP53ALDH1A1 | |
| SCHEMBL10340777 | 0.75 | ALDH1A1 (0.47) | CA2TSHRCA1TP53ALDH1A1 | |
| SCHEMBL78717 | 0.75 | ALDH1A1 (0.47) | CA2TSHRCA1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807758-B2 | Siloxane polymer and method of producing siloxane polymer | JNC CORPORATION (JP) | 2023-11-07 | — | — | US | disclosed |
| US-20210238419-A1 | SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER | JNC CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |