SCHEMBL3922211

SCHEMBL3922211

C=C[Si](CCCOCC1CO1)(OC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GLA P06280 1/20 0.34
MGLL Q99685 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3914380 0.88 SMN1; SMN2 (0.41) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL11290142 0.81 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL23701339 0.81 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL2018047 0.81 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL6656047 0.79 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL28554486 0.79 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL17373030 0.77 TSHR (0.52) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL9560206 0.77 TSHR (0.49) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL18707711 0.77 TSHR (0.47) TSHRSMN1; SMN2ALDH1A1TDP1MEN1
SCHEMBL18094268 0.77 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2468682-B1 Method for producing zirconia sol NISSAN CHEMICAL IND LTD (JP) 2014-01-15 EP disclosed
EP-1798201-B1 METHOD FOR PRODUCING METAL OXIDE SOL NISSAN CHEMICAL IND LTD (JP) 2013-04-03 EP disclosed
EP-2468682-A1 Method for producing zirconia sol Nissan Chemical Industries, Ltd. (JP) 2012-06-27 EP disclosed
US-7553474-B2 Heating metal compound in aqueous medium with quaternary ammonium carbonate; hydrothermal processing; hydrolysis; uniform particle size distribution; oxides of aluminum, yttrium, magnesium, calcium, barium, zinc, nickel, indium, iron, cobalt, cerium, bismuth, titanium, zirconium, silicon, and/or tin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-06-30 US disclosed
US-20080138272-A1 Heating metal compound in aqueous medium with quaternary ammonium carbonate; hydrothermal processing; hydrolysis; uniform particle size distribution; oxides of aluminum, yttrium, magnesium, calcium, barium, zinc, nickel, indium, iron, cobalt, cerium, bismuth, titanium, zirconium, silicon, and/or tin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2008-06-12 US disclosed
EP-1798201-A1 METHOD FOR PRODUCING METAL OXIDE SOL Nissan Chemical Industries, Ltd. (JP) 2007-06-20 EP disclosed