Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 9/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23701434 | 0.89 | KDM4E (0.41) | KDM4EALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL23732563 | 0.87 | KDM4E (0.50) | KDM4EALDH1A1FAAHCYP2C19ABHD6 | |
| SCHEMBL23701390 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL23701483 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1FAAHCYP2C19ABHD6 | |
| SCHEMBL23732566 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1FAAHCYP2C19ABHD6 | |
| SCHEMBL23701387 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL22014811 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1FAAH | |
| SCHEMBL23701399 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL27400160 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1FAAHCYP2C19MAPK1 | |
| SCHEMBL23199735 | 0.79 | AKR1C3 (0.42) | ALDH1A1CYP2C19MAPK1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365984-B | LOX inhibitors | 癌症研究协会皇家癌症医院 | 2024-10-15 | — | — | CN | disclosed |
| US-20210238179-A1 | HEXAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES USEFUL AS LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238179-A1 | HEXAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES USEFUL AS LOX INHIBITORS | LOX, LOXL1, LOXL3 | KDM4E 685/4885ALDH1A1 765/4885FAAH 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.