Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.39 |
| ▸ | DRD3 | P35462 | 13/20 | 0.39 |
| ▸ | DRD4 | P21917 | 7/20 | 0.39 |
| ▸ | DRD1 | P21728 | 5/20 | 0.39 |
| ▸ | DRD5 | P21918 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 9/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23706101 | 1.00 | DRD2 (0.39) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30041995 | 1.00 | DRD2 (0.39) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL23705966 | 0.89 | KDR (0.36) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30041471 | 0.89 | KDR (0.36) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL23705968 | 0.89 | KDR (0.36) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL26141410 | 0.86 | USP30 (0.37) | DRD4KMT2ASLC6A4ALDH1A1MAPK1 | |
| SCHEMBL26141541 | 0.84 | ALDH1A1 (0.34) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL26141426 | 0.82 | ALDH1A1 (0.32) | ALDH1A1HPGD | |
| SCHEMBL26141382 | 0.82 | PRKAA2 (0.32) | ALDH1A1MAPK1 | |
| SCHEMBL26141430 | 0.82 | KDR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12441726-B2 | Compounds and uses thereof | FOGHORN THERAPEUTICS, INC. (US) | 2025-10-14 | — | — | US | disclosed |
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20230145003-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-11 | — | — | US | disclosed |
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-115297861-A | Compound and use thereof | 福宏治疗公司 | 2022-11-04 | — | — | CN | disclosed |
| WO-2021155320-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441726-B2 | Compounds and uses thereof | VHL, CLN6, TFEB | DRD2 4549/4885DRD3 4589/4885DRD4 4588/4885 |
| US-20230145003-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | DRD2 4549/4885DRD3 4589/4885DRD4 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.