⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27442823 | 0.97 | P2RX7 (0.46) | — | |
| SCHEMBL10373456 | 0.75 | P2RX7 (0.52) | — | |
| SCHEMBL5086411 | 0.75 | P2RX7 (0.52) | — | |
| SCHEMBL2169832 | 0.73 | — | — | |
| SCHEMBL27677548 | 0.73 | NAPRT (0.50) | — | |
| SCHEMBL108190 | 0.73 | — | — | |
| SCHEMBL14782157 | 0.72 | NAPRT (0.41) | — | |
| SCHEMBL30368390 | 0.71 | KMO (0.37) | — | |
| SCHEMBL21173935 | 0.71 | KMO (0.37) | — | |
| SCHEMBL353451 | 0.71 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819455-A | Acyl phosphine oxide compound and preparation method thereof | 南方科技大学 | 2023-03-21 | — | — | CN | claimed |
| EP-3216798-A2 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2017-09-13 | — | — | EP | claimed |
| US-20140005133-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2014-01-02 | — | — | US | claimed |
| EP-2673285-A1 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2013-12-18 | — | — | EP | claimed |
| CN-103384676-A | Ketolactone compounds | WOCKHARDT LTD | 2013-11-06 | — | — | CN | claimed |
| WO-2012076989-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2012-06-14 | — | — | WO | claimed |
| CN-115819455-B | Acylphosphine oxide compound and preparation method thereof | 南方科技大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-111050765-B | Spiro compounds and methods of making and using the same | H.隆德贝克有限公司 | 2024-01-02 | — | — | CN | disclosed |
| EP-3675847-B1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H LUNDBECK AS (DK) | 2023-07-12 | — | — | EP | disclosed |
| EP-3675847-B1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H LUNDBECK AS (DK) | 2023-07-12 | — | — | EP | disclosed |
| CN-116348468-A | CFTR modulator compounds, compositions and uses thereof | 日东制药株式会社 | 2023-06-27 | — | — | CN | disclosed |
| WO-2023110473-A1 | HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS | BASF SE (DE) | 2023-06-22 | — | — | WO | disclosed |
| EP-4198033-A1 | HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS | BASF SE (DE) | 2023-06-21 | — | — | EP | disclosed |
| US-6107295-A | Arylalkanoyl pyridazines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-08-22 | — | — | US | disclosed |
| CN-1227547-A | Arylalkanoylpyridazines | MERCK PATENT GMBH (DE) | 1999-09-01 | — | — | CN | disclosed |
| US-5859008-A | Arylalkyl diazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-01-12 | — | — | US | disclosed |
| CN-1157287-A | Arylalkyl diazinones | MERCK PATENT GMBH (DE) | 1997-08-20 | — | — | CN | disclosed |
| CN-1100425-A | Thiazolopyrimidine derivatives | DAIICHI SEIYAKU CO (JP) | 1995-03-22 | — | — | CN | disclosed |
| EP-0316491-A1 | Herbicidal 2-pyridyl and 2-pyrimidine carbonyl 1,3-cyclohexanediones | STAUFFER AGRICULTURAL CHEMICALS COMPANY, INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| US-4708732-A | 2-(pyrimidinecarbonyl)-1,3-cyclohexanediones and their use as herbicidal agents | STAUFFER CHEMICAL COMPANY (US) | 1987-11-24 | — | — | US | disclosed |