Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960459 | 0.83 | AGXT (0.62) | PRMT6AGXTKDM4EMEN1ALDH1A1 | |
| SCHEMBL6268645 | 0.81 | PRMT6 (0.63) | PRMT6AGXTKDM4EMEN1ALDH1A1 | |
| SCHEMBL28216220 | 0.80 | AGXT (0.57) | PRMT6AGXTKDM4EMEN1ALDH1A1 | |
| SCHEMBL10244433 | 0.74 | PRMT6 (0.61) | PRMT6AGXTKDM4EMEN1ALDH1A1 | |
| SCHEMBL24026846 | 0.73 | CHKA (0.68) | PRMT6AGXTALOX5HTR7CHKA | |
| SCHEMBL166575 | 0.73 | PRMT6 (0.65) | PRMT6AGXTKDM4EMEN1ALDH1A1 | |
| SCHEMBL11891932 | 0.72 | AGXT (0.65) | PRMT6AGXTALOX5CFTRHTR7 | |
| SCHEMBL4480384 | 0.72 | PRMT6 (0.68) | PRMT6AGXTKDM4EMEN1ALDH1A1 | |
| SCHEMBL19601451 | 0.70 | PRMT6 (0.57) | PRMT6AGXTKDM4EMEN1ALDH1A1 | |
| SCHEMBL4806907 | 0.70 | AGXT (0.58) | PRMT6AGXTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401276-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | Eisai R&D Management Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010098487-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |