Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 3/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.57 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 3/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238064 | 0.86 | HTR7 (0.51) | AGXTALDH1A1MAPTDRD2DRD3 | |
| SCHEMBL3960459 | 0.85 | AGXT (0.62) | AGXTPRMT6L3MBTL3L3MBTL1KDM4E | |
| SCHEMBL5686209 | 0.85 | HTR7 (0.57) | ALDH1A1MAPTDRD2DRD3HTR7 | |
| SCHEMBL6268645 | 0.84 | PRMT6 (0.63) | AGXTPRMT6L3MBTL3L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL5673049 | 0.83 | AGXT (0.60) | AGXTMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL10244433 | 0.82 | PRMT6 (0.61) | AGXTPRMT6L3MBTL3L3MBTL1KDM4E | |
| SCHEMBL28216220 | 0.81 | AGXT (0.57) | AGXTPRMT6L3MBTL3L3MBTL1KDM4E | |
| SCHEMBL2554494 | 0.80 | ALDH1A1 (0.55) | AGXTPRMT6L3MBTL3L3MBTL1KDM4E | |
| SCHEMBL27526754 | 0.80 | PRMT6 (0.55) | AGXTPRMT6L3MBTL3L3MBTL1KDM4E | |
| SCHEMBL4808902 | 0.79 | L3MBTL3 (0.72) | AGXTPRMT6L3MBTL3L3MBTL1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320973-B2 | Dihydrodiaryloxazepine derivative and pharmaceutical composition containing the same | AJINOMOTO CO., INC. (JP) | 2008-01-22 | — | — | US | disclosed |
| US-20040110742-A1 | Dihydrodiaryloxazepine derivative and pharmaceutical composition containing the same | AJINOMOTO CO., INC. (JP) | 2004-06-10 | — | — | US | disclosed |
| EP-1403258-A1 | DIHYDRODIARYLOXAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110742-A1 | Dihydrodiaryloxazepine derivative and pharmaceutical composition containing the same | CYP3A4, PPARD, CYP4B1 | AGXT 2185/4885PRMT6 3517/4885L3MBTL3 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.