Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29994198 | 1.00 | ROCK2 (0.39) | ROCK2CHRNA7ALDH1A1KDM4EMEN1 | |
| SCHEMBL23704277 | 0.87 | MAPT (0.43) | CHRNA7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23707374 | 0.84 | ERCC1 (0.41) | CHRNA7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23707339 | 0.80 | CHRNA7 (0.37) | CHRNA7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23707338 | 0.79 | CHRNA7 (0.37) | CHRNA7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23707342 | 0.79 | MAPT (0.38) | CHRNA7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23707380 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL23707387 | 0.78 | MAPT (0.37) | CHRNA7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23704107 | 0.78 | ALDH1A1 (0.37) | CHRNA7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29994016 | 0.78 | ALDH1A1 (0.37) | CHRNA7ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052860-B | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2021154902-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-08-05 | — | — | WO | disclosed |