SCHEMBL23704277

SCHEMBL23704277

Cc1c(C2CCOCC2)[nH]c2ccc(CNC(=O)O)cc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.43
▸ MEN1 O00255 6/20 0.43
▸ KMT2A Q03164 6/20 0.43
▸ ALDH1A1 P00352 6/20 0.43
▸ KDM4E B2RXH2 6/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ CASP1 P29466 1/20 0.43
▸ CASP7 P55210 1/20 0.43
▸ CHRNA7 P36544 1/20 0.41
▸ GAA P10253 2/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ HPGD P15428 3/20 0.39
▸ CASP6 P55212 1/20 0.39
▸ EGFR P00533 1/20 0.39
▸ CDK2 P24941 1/20 0.39
▸ HTT P42858 3/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ MTNR1A P48039 1/20 0.37
▸ MTNR1B P49286 1/20 0.37
▸ LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23707374 0.90 ERCC1 (0.41) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL23707403 0.87 ROCK2 (0.39) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL29994198 0.87 ROCK2 (0.39) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL23704307 0.86 KDM4E (0.52) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL29994897 0.86 KDM4E (0.52) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL23707380 0.85 ALDH1A1 (0.42) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL23707339 0.84 CHRNA7 (0.37) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL23707297 0.84 RAB9A (0.37) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL23707387 0.84 MAPT (0.37) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL23704107 0.84 ALDH1A1 (0.37) MAPTMEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230116201-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-04-13 — — US disclosed
EP-4097084-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2022-12-07 — — EP disclosed
WO-2021154902-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-08-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230116201-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 MAPT 3292/4885MEN1 2636/4885KMT2A 3819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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