SCHEMBL23707406

SCHEMBL23707406

O=Cc1ccc(N2CCc3ccccc32)s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.50
LMNA P02545 1/20 0.50
MAPK1 P28482 1/20 0.50
ACKR3 P25106 2/20 0.46
SRD5A1 P18405 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
RXFP1 Q9HBX9 1/20 0.40
ROCK1 Q13464 1/20 0.39
TSHR P16473 4/20 0.39
ALOX15 P16050 2/20 0.39
BRCA1 P38398 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23707404 0.76 LMNA (0.40) TP53LMNAMAPK1ACKR3SRD5A1
SCHEMBL19603636 0.74 HPGD (0.41) ALDH1A1HPGDNOTUMPOLBMAPT
SCHEMBL28004411 0.73 SRD5A1 (0.46) TP53LMNAMAPK1SRD5A1SMN1; SMN2
SCHEMBL31023242 0.71 ALDH1A1 (0.45) TP53LMNAMAPK1SRD5A1SMN1; SMN2
SCHEMBL16150235 0.71 ALDH1A1 (0.45) TP53LMNAMAPK1SRD5A1SMN1; SMN2
SCHEMBL23707405 0.70 TSHR (0.49) TP53LMNAMAPK1ACKR3SRD5A1
SCHEMBL23699574 0.68 SRD5A1 (0.41) TP53LMNAMAPK1SRD5A1SMN1; SMN2
SCHEMBL18003041 0.68 ALDH1A1 (0.45) TP53LMNAMAPK1SRD5A1SMN1; SMN2
SCHEMBL28218558 0.68 TSHR (0.42) TP53LMNAMAPK1SRD5A1SMN1; SMN2
SCHEMBL11446362 0.67 SRD5A1 (0.43) TP53LMNAMAPK1SRD5A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858841-A1 COMPOUND AND PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2021-08-04 EP disclosed