SCHEMBL23707404

SCHEMBL23707404

CC1(C)C(=O)C(=Cc2ccc(N3CCc4ccccc43)s2)C(=O)C(C)(C)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
TP53 P04637 1/20 0.40
MAPK1 P28482 1/20 0.40
ACKR3 P25106 2/20 0.39
SRD5A1 P18405 2/20 0.37
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
BRCA1 P38398 1/20 0.36
MAPT P10636 3/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ALDH1A1 P00352 6/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.36
GSK3B P49841 6/20 0.35
GSK3A P49840 1/20 0.35
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23707406 0.76 TP53 (0.50) LMNATP53MAPK1ACKR3SRD5A1
SCHEMBL24965733 0.64 KMT2A (0.49) LMNATP53MAPTNPC1RAB9A
SCHEMBL19629775 0.61 KMT2A (0.52) LMNATP53MAPK1MAPTNPC1
SCHEMBL23707405 0.60 TSHR (0.49) LMNATP53MAPK1ACKR3SRD5A1
SCHEMBL1949315 0.60 ACKR3 (0.76) LMNAMAPK1ACKR3MAPTNPC1
SCHEMBL19603545 0.60 MAPT (0.51) MAPTNPC1RAB9AALDH1A1MEN1
SCHEMBL19603601 0.59 MEN1 (0.38) LMNATP53MAPK1MAPTNPC1
SCHEMBL24618728 0.59 LMNA (0.40) LMNATP53MAPK1MAPTRAB9A
SCHEMBL19603572 0.59 MEN1 (0.40) LMNATP53MAPK1MAPTNPC1
SCHEMBL25026229 0.58 ALDH1A1 (0.55) LMNATP53MAPK1SRD5A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210246134-A1 COMPOUND AND PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-08-12 US disclosed
EP-3858841-A1 COMPOUND AND PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2021-08-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246134-A1 COMPOUND AND PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING THE SAME NCS1, PPOX, CRY1 LMNA 4574/4885TP53 2820/4885MAPK1 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.