Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26774779 | 0.80 | ACACB (0.42) | CYP11B2 | |
| SCHEMBL26774753 | 0.71 | LIPG (0.40) | CLK4ALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL3688350 | 0.71 | ALDH1A1 (0.52) | CLK4ALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL3690932 | 0.71 | HRH3 (0.47) | ALDH1A1KDM2BL3MBTL1 | |
| SCHEMBL26620770 | 0.69 | LIPG (0.56) | LMNAMAPTL3MBTL1 | |
| SCHEMBL23702835 | 0.69 | LIPG (0.56) | LMNAMAPTL3MBTL1 | |
| SCHEMBL26775396 | 0.69 | ACACB (0.39) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL26774735 | 0.69 | LIPG (0.45) | ALDH1A1MAPK1MEN1KMT2AKDM4E | |
| SCHEMBL26774731 | 0.69 | LIPG (0.45) | ALDH1A1MAPK1MEN1KMT2AKDM4E | |
| SCHEMBL3698002 | 0.68 | MAPT (0.46) | CLK4ALDH1A1CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |