Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 4/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.39 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688350 | 0.82 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3681137 | 0.76 | SMYD2 (0.36) | HRH3PDCD1CD274KDM2BL3MBTL3 | |
| SCHEMBL3698002 | 0.76 | MAPT (0.46) | L3MBTL1ALDH1A1SMYD2 | |
| SCHEMBL3690597 | 0.74 | PTPN1 (0.36) | HRH3PDCD1CD274KDM2BL3MBTL3 | |
| SCHEMBL3681135 | 0.74 | PTPN1 (0.36) | HRH3PDCD1CD274KDM2BL3MBTL3 | |
| SCHEMBL23708166 | 0.71 | MAP4K4 (0.44) | KDM2BL3MBTL1ALDH1A1 | |
| SCHEMBL26774779 | 0.71 | ACACB (0.42) | — | |
| SCHEMBL6449542 | 0.70 | ACHE (0.36) | HRH3L3MBTL3L3MBTL1MBTD1ALDH1A1 | |
| SCHEMBL18983420 | 0.70 | APP (0.41) | HRH3PDCD1CD274KDM2BL3MBTL3 | |
| SCHEMBL4601494 | 0.70 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1MBTD1SMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |