Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24526057 | 0.85 | HDAC1 (0.46) | LDHARAB9ANPC1PDGFRBFLT3 | |
| SCHEMBL14985522 | 0.83 | RAB9A (0.54) | LDHARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL15490820 | 0.82 | LDHA (0.51) | LDHARAB9ANPC1PDGFRBKDR | |
| SCHEMBL29507311 | 0.82 | LDHA (0.62) | LDHARAB9ANPC1PDGFRBKDR | |
| SCHEMBL2481915 | 0.82 | LDHA (0.62) | LDHARAB9ANPC1PDGFRBKDR | |
| SCHEMBL15006255 | 0.80 | POLB (0.54) | LDHARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16906529 | 0.79 | HDAC1 (0.47) | KDM4EALDH1A1IDO1TDO2ALOX5AP | |
| SCHEMBL13140208 | 0.79 | ALOX5AP (0.46) | LDHAFLT3ALDH1A1ALOX5APFEN1 | |
| SCHEMBL19454849 | 0.78 | LDHA (0.59) | LDHARAB9ANPC1PDGFRBKDR | |
| SCHEMBL117744 | 0.78 | LDHA (0.64) | LDHARAB9ANPC1PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |