SCHEMBL24526057

SCHEMBL24526057

Cc1ccc(-c2cc(C)c(F)cn2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.46
CYP11B1 P15538 2/20 0.43
CYP11B2 P19099 2/20 0.43
LDHA P00338 1/20 0.41
AURKA O14965 1/20 0.41
ABL1 P00519 1/20 0.41
NTRK1 P04629 1/20 0.41
LCK P06239 1/20 0.41
CSF1R P07333 1/20 0.41
RET P07949 1/20 0.41
MET P08581 1/20 0.41
PDGFRB P09619 1/20 0.41
PIM1 P11309 1/20 0.41
PDGFRA P16234 1/20 0.41
FLT3 P36888 1/20 0.41
MAPK8 P45983 1/20 0.41
CDK8 P49336 1/20 0.41
MAP2K1 Q02750 1/20 0.41
MAP4K2 Q12851 1/20 0.41
ROCK1 Q13464 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23708708 0.85 LDHA (0.57) CYP11B1CYP11B2LDHAPDGFRBFLT3
SCHEMBL24523706 0.85 CYP11B1 (0.43) HDAC1CYP11B1CYP11B2LDHAAURKA
SCHEMBL16906529 0.82 HDAC1 (0.47) HDAC1CYP11B1CYP11B2KDM1ALMNA
SCHEMBL18729621 0.82 CCR1 (0.44) LDHAAURKAABL1NTRK1LCK
SCHEMBL2187669 0.78 LDHA (0.46) LDHAPTGS2CCR1CCR5CCR8
SCHEMBL27157143 0.77 LDHA (0.41) HDAC1LDHAABL1RETAURKB
SCHEMBL30819263 0.77 LDHA (0.41) HDAC1LDHAABL1RETAURKB
SCHEMBL16906530 0.76 TRPV3 (0.44)
SCHEMBL18729745 0.76 LDHA (0.40) LDHACCR1CCR5CCR8HDAC6
SCHEMBL25755553 0.74 TDO2 (0.45) LDHAAURKAABL1NTRK1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220199916-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-06-23 US disclosed