Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | RAB7A | P51149 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | CDC42 | P60953 | 1/20 | 0.53 |
| ▸ | RAB2A | P61019 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096464 | 0.82 | RAB7A (0.78) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL15272485 | 0.78 | KDM4E (0.72) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL15272139 | 0.78 | ALDH1A1 (0.84) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL13438095 | 0.77 | ALDH1A1 (0.84) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL15832860 | 0.75 | RAB7A (0.84) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL15273119 | 0.74 | ALDH1A1 (0.69) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL15832892 | 0.74 | CXCR2 (0.70) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL15832879 | 0.74 | RAB7A (0.76) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL3489776 | 0.72 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL13438087 | 0.71 | ALDH1A1 (0.74) | ALDH1A1MAPTKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230132397-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230132397-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-04-27 | — | — | US | disclosed |
| US-20220118085-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-04-21 | — | — | US | disclosed |
| US-20210236632-A1 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118085-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | TLR2, TLR1, TLR3 | ALDH1A1 4565/4885MAPT 206/4885KMT2A 2910/4885 |
| US-20230132397-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | TLR2, TLR1, TLR3 | ALDH1A1 4565/4885MAPT 206/4885KMT2A 2910/4885 |
| US-20210236632-A1 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | TLR2, TLR1, TLR3 | ALDH1A1 4565/4885MAPT 206/4885KMT2A 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.