Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816138 | 0.83 | ALDH1A1 (0.67) | ALDH1A1ATMMEN1KMT2AMAPT | |
| SCHEMBL27996198 | 0.78 | ALDH1A1 (0.60) | ALDH1A1ATMMEN1KMT2AMAPT | |
| SCHEMBL12482090 | 0.74 | PTGER1 (0.74) | PTGER1THRB | |
| SCHEMBL12407356 | 0.74 | PTGER1 (0.74) | ALDH1A1MEN1KMT2APTGER1THRB | |
| SCHEMBL11224504 | 0.73 | MEN1 (0.52) | ALDH1A1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL3401540 | 0.72 | MEN1 (0.63) | ALDH1A1MEN1KMT2AMAPTPTGER1 | |
| SCHEMBL24279545 | 0.72 | MEN1 (0.54) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27996173 | 0.72 | MAPT (0.60) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14679143 | 0.72 | KMT2A (0.57) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16265424 | 0.72 | ALDH1A1 (0.52) | ALDH1A1ATMMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230132397-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-04-27 | — | — | US | disclosed |
| US-20220118085-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-04-21 | — | — | US | disclosed |
| US-20210236632-A1 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118085-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | TLR2, TLR1, TLR3 | ALDH1A1 4565/4885ATM 798/4885MEN1 4788/4885 |
| US-20230132397-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | TLR2, TLR1, TLR3 | ALDH1A1 4565/4885ATM 798/4885MEN1 4788/4885 |
| US-20210236632-A1 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | TLR2, TLR1, TLR3 | ALDH1A1 4565/4885ATM 798/4885MEN1 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.