Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23711763 | 0.93 | HDAC2 (0.41) | HPGDALDH1A1TP53SMN1; SMN2RAB9A | |
| SCHEMBL23711720 | 0.91 | TDP1 (0.45) | HPGDALDH1A1TP53SMN1; SMN2RAB9A | |
| SCHEMBL23506334 | 0.91 | HPGD (0.48) | HPGDALDH1A1TP53SMN1; SMN2RAB9A | |
| SCHEMBL21702241 | 0.91 | HPGD (0.48) | HPGDALDH1A1TP53SMN1; SMN2RAB9A | |
| SCHEMBL26498717 | 0.88 | CTSS (0.47) | CTSL | |
| SCHEMBL26494883 | 0.87 | CTSL (0.41) | HPGDALDH1A1TP53SMN1; SMN2CTSL | |
| SCHEMBL21702237 | 0.86 | HPGD (0.50) | HPGDALDH1A1TP53SMN1; SMN2RAB9A | |
| SCHEMBL23711629 | 0.86 | HPGD (0.50) | HPGDALDH1A1TP53SMN1; SMN2RAB9A | |
| SCHEMBL23506229 | 0.86 | HPGD (0.50) | HPGDALDH1A1TP53SMN1; SMN2RAB9A | |
| SCHEMBL23711733 | 0.86 | TP53 (0.52) | HPGDALDH1A1TP53SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151387-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | 中国科学院上海药物研究所 | 2021-08-05 | — | — | WO | disclosed |