SCHEMBL23712495

SCHEMBL23712495

CO/C=C(\C)Oc1cc(Oc2ccccc2)ccc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.41
NR1H4 Q96RI1 1/20 0.39
PGR P06401 1/20 0.37
NR1H2 P55055 1/20 0.37
BAX Q07812 1/20 0.37
AR P10275 1/20 0.37
SRD5A2 P31213 1/20 0.36
ERN1 O75460 1/20 0.36
NTRK1 P04629 1/20 0.36
IGF1R P08069 1/20 0.36
FGFR1 P11362 1/20 0.36
NTRK2 Q16620 1/20 0.36
TLR4 O00206 1/20 0.36
TLR2 O60603 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26418773 0.81 SMN1; SMN2 (0.40) NR1H4PGRSRD5A2HPGDSMN1; SMN2
SCHEMBL23712440 0.78 FFAR1 (0.44) SMN1; SMN2MAPTTDP1MEN1KMT2A
SCHEMBL14586633 0.77 LTA4H (0.57) LTA4HARERN1NTRK1IGF1R
SCHEMBL424805 0.77 LTA4H (0.50) LTA4HNR1H2BAXARSMN1; SMN2
SCHEMBL23712502 0.77 LTB4R (0.38)
SCHEMBL23712438 0.76 ATM (0.41) SMN1; SMN2MAPTTDP1L3MBTL1TSHR
SCHEMBL23712641 0.75 LTA4H (0.40) LTA4HMAPTTDP1L3MBTL1MEN1
SCHEMBL23712623 0.75 ALDH1A1 (0.38) ARHPGDSMN1; SMN2MAPTMEN1
SCHEMBL23712452 0.71 ALDH1A1 (0.47) HPGDSMN1; SMN2MAPTTDP1TSHR
SCHEMBL7038743 0.71 LTA4H (0.57) LTA4HARSMN1; SMN2L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021153782-A1 METHOD FOR CONTROLLING PHAKOPSORA PACHYRHIZI HAVING RESISTANCE AGAINST QoI FUNGICIDE 住友化学株式会社 2021-08-05 WO disclosed