Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21698491 | 0.83 | NOTUM (0.42) | — | |
| SCHEMBL23712709 | 0.81 | — | — | |
| SCHEMBL24038257 | 0.80 | RXRA (0.35) | — | |
| SCHEMBL22082980 | 0.78 | TP53 (0.38) | — | |
| SCHEMBL18428330 | 0.77 | L3MBTL1 (0.38) | TSHRMAPK1 | |
| SCHEMBL18428342 | 0.76 | PTGS1 (0.35) | — | |
| SCHEMBL21125863 | 0.75 | GABRA1 (0.40) | — | |
| SCHEMBL23712500 | 0.75 | — | — | |
| SCHEMBL24038361 | 0.75 | RXRA (0.43) | — | |
| SCHEMBL24038109 | 0.75 | RXRA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021152165-A1 | MACROCYCLIC RIP2-KINASE INHIBITORS | ONCODESIGN S.A. (FR) | 2021-08-05 | — | — | WO | disclosed |