Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413300 | 0.82 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL30104052 | 0.82 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL23702657 | 0.82 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL23702646 | 0.82 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL873113 | 0.80 | MAPT (0.53) | MAPTALDH1A1KMT2AMEN1KAT6A | |
| SCHEMBL14964128 | 0.80 | MAPT (0.49) | MAPTALDH1A1KMT2AMEN1KAT6A | |
| SCHEMBL2643542 | 0.78 | KEAP1 (0.52) | TSHRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL16342745 | 0.77 | SMN1; SMN2 (0.50) | TSHRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4449726 | 0.76 | NOTUM (0.55) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL10383600 | 0.75 | ALDH1A1 (0.47) | TSHRMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021152165-A1 | MACROCYCLIC RIP2-KINASE INHIBITORS | ONCODESIGN S.A. (FR) | 2021-08-05 | — | — | WO | disclosed |