Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23702646 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EMAPK1KEAP1 | |
| SCHEMBL31413300 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EMAPK1KEAP1 | |
| SCHEMBL23712697 | 0.82 | TSHR (0.50) | ALDH1A1LMNAKDM4EMAPK1MEN1 | |
| SCHEMBL23702657 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EMAPK1KEAP1 | |
| SCHEMBL2643542 | 0.78 | KEAP1 (0.52) | ALDH1A1LMNAKDM4EKEAP1NFE2L2 | |
| SCHEMBL4449726 | 0.76 | NOTUM (0.55) | ALDH1A1LMNAKDM4EMAPK1NOTUM | |
| SCHEMBL22686997 | 0.74 | HSPB1 (0.52) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL16342745 | 0.74 | SMN1; SMN2 (0.50) | ALDH1A1LMNANPC1RAB9AMEN1 | |
| SCHEMBL23702605 | 0.72 | NOTUM (0.42) | ALDH1A1LMNAKDM4EMAPK1NOTUM | |
| SCHEMBL30104024 | 0.72 | NOTUM (0.42) | ALDH1A1LMNAKDM4EMAPK1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698020-B | Macrocyclic RIP 2-kinase inhibitors | 昂科迪塞恩精密医药公司(OPM) | 2025-02-25 | — | — | CN | disclosed |
| EP-4097110-A1 | MACROCYCLIC RIP2-KINASE INHIBITORS | Oncodesign S.A. (FR) | 2022-12-07 | — | — | EP | disclosed |