Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 14/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204878 | 0.80 | MCL1 (0.39) | MPO | |
| SCHEMBL205462 | 0.76 | MPO (0.60) | MPOATMPTGER4 | |
| SCHEMBL18073164 | 0.76 | MPO (0.91) | MPOATM | |
| SCHEMBL13030180 | 0.74 | MPO (0.65) | MPOATMPTGER4 | |
| SCHEMBL20132949 | 0.70 | MPO (0.61) | MPOATM | |
| SCHEMBL202865 | 0.68 | MPO (0.57) | MPOATM | |
| SCHEMBL15881958 | 0.66 | ELANE (0.54) | PTGER4 | |
| SCHEMBL11442537 | 0.65 | APAF1 (0.68) | — | |
| SCHEMBL15882075 | 0.63 | TSHR (0.51) | PTGER4 | |
| SCHEMBL17324748 | 0.63 | HTR3A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364301-A1 | ENANTIOMERICALLY ENRICHED ARYLOAZOL- 2 -YL CYANOETHYLAMINO PARACITICIDAL COMPOUNDS | Merial Limited (US) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010056999-A1 | ENANTIOMERICALLY ENRICHED ARYLOAZOL- 2 -YL CYANOETHYLAMINO PARACITICIDAL COMPOUNDS | MERIAL LIMITED (US) | 2010-05-20 | — | — | WO | disclosed |