Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21524281 | 0.83 | MAOB (0.51) | CYP19A1MIFC1R | |
| SCHEMBL27935835 | 0.83 | MEN1 (0.44) | CYP19A1KDM4EHPGDMIFGLA | |
| SCHEMBL23713558 | 0.82 | RAB9A (0.53) | CYP19A1TRPA1KDM4EHPGDGLA | |
| SCHEMBL30568051 | 0.82 | S1PR1 (0.41) | CYP19A1KDM4EHPGDMIFGLA | |
| SCHEMBL18523588 | 0.82 | S1PR1 (0.41) | CYP19A1KDM4EHPGDMIFGLA | |
| SCHEMBL22590858 | 0.81 | RAB9A (0.57) | KDM4EHPGDGLATP53NPC1 | |
| SCHEMBL18535489 | 0.81 | MIF (0.65) | KDM4EHPGDMIFGLANPC1 | |
| SCHEMBL18523595 | 0.81 | MAOB (0.51) | CYP19A1KDM4EHPGDMIFTP53 | |
| SCHEMBL18583699 | 0.81 | MIF (0.45) | CYP19A1KDM4EHPGDMIFGLA | |
| SCHEMBL21524279 | 0.80 | NPC1 (0.64) | KDM4EHPGDMIFGLATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078177-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078177-B2 | Compounds for optically active devices | PDE6C, ALDH1A2, PDE6A | CYP19A1 1773/4885TRPA1 16/4885KDM4E 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.