Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713542 | 0.91 | RAB9A (0.51) | RAB9AALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL21524279 | 0.87 | NPC1 (0.64) | RAB9AALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL21761486 | 0.85 | KDM4E (0.48) | RAB9AALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL24046279 | 0.85 | NPC1 (0.49) | RAB9AALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL23713535 | 0.84 | RAB9A (0.51) | RAB9AALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL18535493 | 0.83 | GLA (0.67) | RAB9AALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL7116196 | 0.82 | MIF (0.61) | RAB9AALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL23713472 | 0.82 | CYP19A1 (0.48) | RAB9AALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL22625422 | 0.81 | NPC1 (0.46) | RAB9AALDH1A1SMN1; SMN2GLAMAPT | |
| SCHEMBL18535561 | 0.81 | KDM4E (0.46) | RAB9AALDH1A1SMN1; SMN2GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078177-B2 | Compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078177-B2 | Compounds for optically active devices | PDE6C, ALDH1A2, PDE6A | RAB9A 930/4885ALDH1A1 296/4885SMN1; SMN2 4850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.