SCHEMBL23713626

SCHEMBL23713626

CN1c2ccccc2N(C)c2cc(C(F)(F)F)ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.47
ALDH1A1 P00352 4/20 0.46
PKM P14618 1/20 0.46
TP53 P04637 4/20 0.43
MAPK1 P28482 3/20 0.43
TSHR P16473 3/20 0.43
NPC1 O15118 2/20 0.43
CYP1A2 P05177 2/20 0.43
ABCB1 P08183 2/20 0.43
HTR1A P08908 2/20 0.43
ADRA2A P08913 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
CYP2D6 P10635 2/20 0.43
CHRM1 P11229 2/20 0.43
DRD1 P21728 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
ADRA1A P35348 2/20 0.43
DRD3 P35462 2/20 0.43
THPO P40225 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5070034 0.86 ALDH1A1 (0.41) KIF11ALDH1A1PKMTSHRCYP1A2
SCHEMBL10133838 0.82 NR1H3 (0.46) KIF11ALDH1A1PKMTP53MAPK1
SCHEMBL4996062 0.82 NR1H3 (0.47) KIF11ALDH1A1PKMTSHRNPC1
SCHEMBL16855153 0.80 NR1H2 (0.52) KIF11ALDH1A1PKMTP53MAPK1
SCHEMBL21497978 0.79 ALDH1A1 (0.47) KIF11ALDH1A1PKMTP53MAPK1
SCHEMBL14328384 0.79 MAOA (0.61) ALDH1A1TP53MAPK1TSHRNPC1
SCHEMBL23713627 0.74 NR1H3 (0.44) KIF11ALDH1A1PKMTSHRNPC1
SCHEMBL29390564 0.72 MAOA (0.60) ALDH1A1HTR1AADRA2ADRD1SLC6A2
SCHEMBL4571020 0.72 MAOA (0.60) ALDH1A1HTR1AADRA2ADRD1SLC6A2
SCHEMBL13636983 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210240047-A1 ELECTROCHROMIC COMPOUNDS GENTEX CORPORATION (US) 2021-08-05 US disclosed