Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15492199 | 0.79 | P2RX4 (0.40) | ALDH1A1CYP1A2CYP2D6KIF11SCN9A | |
| SCHEMBL23713626 | 0.79 | KIF11 (0.47) | ALDH1A1KDM4ECYP1A2CYP2D6KIF11 | |
| SCHEMBL47007 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4ERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL31067286 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4ERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL21497997 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4ENR1H2NR1H3RAB9A | |
| Hydrogen Sulfide SCHEMBL28845788 | 0.76 | KDM4E (0.53) | ALDH1A1KDM4ERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL12841614 | 0.76 | KDM4E (0.47) | ALDH1A1KDM4ERAB9ALMNAMAPT | |
| SCHEMBL15489933 | 0.76 | P2RX4 (0.37) | ALDH1A1CYP1A2CYP2D6KIF11SCN9A | |
| SCHEMBL10133785 | 0.75 | NR1H3 (0.48) | ALDH1A1KDM4ENR1H2NR1H3KIF11 | |
| SCHEMBL13445191 | 0.75 | KDM4E (0.46) | ALDH1A1KDM4ERAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450282-B2 | Stereospecific process for 3-heterocyclylcycloaliphatic-1,2-diols | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450282-B2 | Stereospecific process for 3-heterocyclylcycloaliphatic-1,2-diols | DDT, ODC1, CBR1 | ALDH1A1 458/4885KDM4E 3221/4885NR1H2 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.