Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865708 | 0.84 | KMT2A (0.47) | RAB9AGAAMAPTLMNAALDH1A1 | |
| SCHEMBL14289044 | 0.80 | ALDH1A1 (0.49) | HTTRAB9AGAAKDM4EMAPK1 | |
| SCHEMBL10310272 | 0.79 | ALDH1A1 (0.47) | HTTRAB9AGAAMAPK1MAPT | |
| SCHEMBL17178075 | 0.79 | CA9 (0.54) | HTTRAB9AGAAKDM4EMAPK1 | |
| SCHEMBL8039876 | 0.79 | HTT (0.54) | HTTRAB9AGAAKDM4EMAPK1 | |
| SCHEMBL48578 | 0.79 | HTT (0.64) | HTTRAB9AGAAMAPK1MAPT | |
| SCHEMBL13120816 | 0.78 | ALOX12 (0.56) | GAAKDM4EMAPTLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9547056 | 0.78 | HTT (0.49) | HTTRAB9AGAAMAPTLMNA | |
| Hydrochloric Acid SCHEMBL10951495 | 0.78 | HTT (0.49) | HTTRAB9AGAAMAPTLMNA | |
| SCHEMBL13450756 | 0.77 | ALDH1A1 (0.64) | HTTGAAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668871-B1 | 6-AMINO-7,9-DIHYDRO-8H-PURIN-8-ONE DERIVATIVES AS IMMUNOSTIMULANT TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-08-04 | — | — | EP | disclosed |