Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1559659 | 0.82 | KMT2A (0.65) | GAALMNAKMT2ASLC6A2SLC6A4 | |
| SCHEMBL28048727 | 0.80 | POLB (0.48) | GAALMNAKMT2AALDH1A1HPGD | |
| SCHEMBL28858278 | 0.79 | ALDH1A1 (0.47) | GAALMNAKMT2AALDH1A1HPGD | |
| SCHEMBL1805144 | 0.78 | GAA (0.71) | GAAKMT2APLK1ALDH1A1HPGD | |
| SCHEMBL11758277 | 0.78 | AKR1C3 (0.47) | GAALMNAKMT2AALDH1A1MAPT | |
| SCHEMBL5572374 | 0.77 | HPGD (0.51) | GAALMNAKMT2APLK1ALDH1A1 | |
| SCHEMBL8571882 | 0.77 | GAA (0.58) | GAAKMT2APLK1ALDH1A1HPGD | |
| SCHEMBL24445885 | 0.77 | GAA (0.58) | GAALMNAPLK1ALDH1A1TSHR | |
| SCHEMBL16952148 | 0.76 | ALDH1A1 (0.37) | GAALMNAKMT2AALDH1A1HPGD | |
| SCHEMBL145178 | 0.75 | GAA (0.56) | GAAKMT2APLK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155320-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |