SCHEMBL25948773

SCHEMBL25948773

COC(=O)/C(=C/NC1CC1)C(=N)C(=O)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.31
ADH1A P07327 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25948529 0.66 EP300 (0.44)
SCHEMBL21863409 0.65 ADH1B (0.33) ADH1BADH1A
SCHEMBL21863420 0.65 GLO1 (0.43)
SCHEMBL24158818 0.64 ADH1B (0.31) ADH1BADH1A
SCHEMBL24584930 0.64 RECQL (0.44) ADH1BADH1A
SCHEMBL25701709 0.64 ADH1B (0.37) ADH1BADH1A
SCHEMBL23469631 0.64 OPRK1 (0.34)
SCHEMBL11533251 0.64 L3MBTL1 (0.40)
SCHEMBL9490077 0.63 HPGD (0.38)
SCHEMBL9874165 0.63 HPGD (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023133271-A1 BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES NodThera Limited (GB) 2023-07-13 WO disclosed