SCHEMBL23715593

SCHEMBL23715593

CC(=O)/C=C(/O)NC(N)=O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.48
LMNA P02545 2/20 0.33
BLM P54132 2/20 0.33
PMP22 Q01453 2/20 0.33
ALOX15 P16050 1/20 0.33
TAS2R38 P59533 1/20 0.33
TSHR P16473 2/20 0.30
NFKB1 P19838 2/20 0.30
CYP1A2 P05177 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30
CA2 P00918 1/20 0.30
CYP3A4 P08684 1/20 0.30
CA5A P35218 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28316382 0.72 CRBN (0.65) CRBNLMNABLMPMP22ALOX15
SCHEMBL18179232 0.70
SCHEMBL15849949 0.70
SCHEMBL18235744 0.70
SCHEMBL5172272 0.70 CRBN (0.48) CRBNLMNABLMPMP22ALOX15
SCHEMBL5172269 0.70 CRBN (0.48) CRBNLMNABLMPMP22ALOX15
SCHEMBL20053118 0.69
Hydrogen Peroxide SCHEMBL4232421 0.67
SCHEMBL19988063 0.67 CRBN (0.50) CRBNLMNABLMPMP22ALOX15
SCHEMBL28356738 0.67 CRBN (0.50) CRBNLMNABLMPMP22ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210236495-A1 Compounds and Their Use for Reducing Uric Acid Levels ACQUIST LLC (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210236495-A1 Compounds and Their Use for Reducing Uric Acid Levels XDH, OAT, URB2 CRBN 4287/4885LMNA 3224/4885BLM 2693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.