Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLS | O94925 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27300118 | 0.80 | — | — | |
| SCHEMBL20197335 | 0.76 | RAB9A (0.38) | NPC1KDM4EALDH1A1 | |
| SCHEMBL15270399 | 0.70 | GBA1 (0.46) | GBA1NPC1ADRA2AADRA2BADRA2C | |
| SCHEMBL13754672 | 0.67 | KDM4E (0.46) | GBA1NPC1ADRA2AADRA2BADRA2C | |
| SCHEMBL28126589 | 0.67 | ALDH1A1 (0.48) | GBA1NPC1ADRA2AADRA2BADRA2C | |
| SCHEMBL14128749 | 0.67 | NPC1 (0.41) | GBA1NPC1ADRA2AADRA2BADRA2C | |
| SCHEMBL22432863 | 0.66 | CES1 (0.38) | ALDH1A1 | |
| SCHEMBL5686 | 0.65 | ALDH1A1 (0.52) | GBA1NPC1ADRA2AADRA2BADRA2C | |
| SCHEMBL19150888 | 0.65 | GBA1 (0.44) | GBA1NPC1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL3759897 | 0.64 | ALDH1A1 (0.50) | GBA1NPC1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |