Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715798 | 0.76 | EGFR (0.36) | NPC1ALDH1A1KDM4E | |
| SCHEMBL23716291 | 0.75 | ALDH1A1 (0.39) | RAB9ANPC1FDPSHRH3ALDH1A1 | |
| SCHEMBL22432863 | 0.75 | CES1 (0.38) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL18639384 | 0.75 | SMN1; SMN2 (0.50) | RAB9ANPC1ALDH1A1KDM4EMEN1 | |
| SCHEMBL19512759 | 0.72 | RAB9A (0.38) | RAB9ANPC1HRH3ALDH1A1KDM4E | |
| SCHEMBL25108721 | 0.72 | RAB9A (0.38) | RAB9ANPC1HRH3ALDH1A1KDM4E | |
| SCHEMBL28632625 | 0.71 | ALDH1A1 (0.46) | RAB9ANPC1HRH3ALDH1A1HRH1 | |
| SCHEMBL21386868 | 0.69 | HRH1 (0.42) | FDPSHRH3ALDH1A1HRH1SMN1; SMN2 | |
| SCHEMBL11800372 | 0.69 | HRH1 (0.42) | FDPSHRH3ALDH1A1HRH1SMN1; SMN2 | |
| SCHEMBL609979 | 0.69 | RAB9A (0.44) | RAB9ANPC1FDPSHRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |