Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 10/20 | 0.51 |
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14902855 | 0.94 | L3MBTL1 (0.62) | L3MBTL1MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL10101731 | 0.82 | L3MBTL1 (0.68) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10054644 | 0.81 | SMN1; SMN2 (0.50) | L3MBTL1MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL8363638 | 0.81 | SMN1; SMN2 (0.50) | L3MBTL1MAPTALDH1A1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL6648935 | 0.79 | MAOB (0.50) | L3MBTL1MAPTALDH1A1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL6786483 | 0.79 | MAOB (0.50) | L3MBTL1MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL10406690 | 0.76 | ALDH1A1 (0.59) | L3MBTL1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7399653 | 0.75 | NPSR1 (0.50) | L3MBTL1MAPTNPC1RAB9ATDP1 | |
| SCHEMBL23486912 | 0.75 | L3MBTL1 (0.67) | L3MBTL1MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL2755830 | 0.73 | L3MBTL1 (0.50) | L3MBTL1MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |