SCHEMBL7399653

SCHEMBL7399653

CCON=C(N)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
NPC1 O15118 7/20 0.47
RAB9A P51151 7/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
PKM P14618 3/20 0.47
GAA P10253 2/20 0.47
HPGD P15428 2/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
CDK5 Q00535 1/20 0.46
CDK5R1 Q15078 1/20 0.46
LMNA P02545 2/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2B Q13224 1/20 0.46
KMT2A Q03164 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6651594 0.82 LMNA (0.47) L3MBTL1TDP1NPC1RAB9ASMN1; SMN2
SCHEMBL18300591 0.81 ALDH1A1 (0.41) NPSR1L3MBTL1TDP1NPC1RAB9A
SCHEMBL18300592 0.81 ALDH1A1 (0.41) NPSR1L3MBTL1TDP1NPC1RAB9A
SCHEMBL8362518 0.79 LOXL2 (0.46) L3MBTL1TDP1NPC1RAB9ASMN1; SMN2
SCHEMBL13351521 0.79 ALDH1A1 (0.49) L3MBTL1SMN1; SMN2HPGDLMNAMAPK1
Hydrochloric Acid SCHEMBL18300350 0.78 NOS3 (0.44) L3MBTL1NPC1RAB9ASMN1; SMN2GAA
SCHEMBL8448451 0.78 GAA (0.55) NPSR1L3MBTL1TDP1NPC1RAB9A
SCHEMBL22758101 0.78 GAA (0.55) NPSR1L3MBTL1TDP1NPC1RAB9A
Hydrochloric Acid SCHEMBL18300351 0.78 NOS3 (0.44) L3MBTL1NPC1RAB9ASMN1; SMN2GAA
SCHEMBL8448454 0.78 GAA (0.55) NPSR1L3MBTL1TDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210792-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE OF BOTH OF FOREGOING 日本農薬株式会社 2023-11-02 WO disclosed
CN-100567267-C Aramidine derivative, salt thereof, and antifungal agent containing the same TOYAMA CHEMICAL CO LTD (JP) 2009-12-09 CN disclosed
US-5330990-A Antagonists of 5-HT and 5-HT3 receptors, psychological disorders, antinausea NOVO NORDISK A/S (DK) 1994-07-19 US disclosed
EP-0419397-B1 Substituted urea compounds and their preparation and use NOVO NORDISK AS (DK) 1994-06-08 EP disclosed
EP-0491770-A1 SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1992-07-01 EP disclosed
EP-0419397-A1 Substituted urea compounds and their preparation and use NOVO NORDISK A/S (DK) 1991-03-27 EP disclosed
WO-1991003475-A1 SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1991-03-21 WO disclosed