Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716174 | 0.89 | AR (0.44) | ARNPC1RAB9ATP53HSD17B10 | |
| SCHEMBL7934186 | 0.79 | AR (0.46) | ARNPC1RAB9ATP53HSD17B10 | |
| SCHEMBL11843714 | 0.78 | MAOB (0.59) | ARNPC1RAB9ATP53HSD17B10 | |
| SCHEMBL7929558 | 0.77 | AR (0.44) | ARNPC1RAB9ATP53HSD17B10 | |
| SCHEMBL5901307 | 0.76 | MAOB (0.48) | ARNPC1RAB9ATP53HSD17B10 | |
| SCHEMBL4694901 | 0.75 | AR (0.57) | ARRAB9AXDHALDH1A1HPGD | |
| SCHEMBL4673630 | 0.75 | KDM4E (0.51) | ARNPC1RAB9ATP53HSD17B10 | |
| SCHEMBL5902106 | 0.75 | MAOB (0.78) | ARMAOBMAOAXDH | |
| SCHEMBL22272202 | 0.73 | TRPV4 (0.47) | ARHSD17B10XDHALDH1A1HPGD | |
| SCHEMBL5901353 | 0.73 | XDH (0.46) | ARNPC1RAB9AXDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |