Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716218 | 0.78 | RECQL (0.36) | TSHRSLC22A12 | |
| SCHEMBL509379 | 0.77 | AR (0.50) | ARMRGPRX4TSHRPGR | |
| SCHEMBL23716174 | 0.76 | AR (0.44) | AR | |
| SCHEMBL25680960 | 0.76 | AR (0.44) | ARMRGPRX4TSHRSLC22A12ESRRA | |
| SCHEMBL6946306 | 0.75 | AR (0.47) | ARMRGPRX4PGR | |
| SCHEMBL23716298 | 0.74 | CYP1A2 (0.45) | ARS1PR3S1PR1 | |
| SCHEMBL6110658 | 0.74 | AR (0.43) | ARMRGPRX4TSHRSLC22A12ESRRA | |
| SCHEMBL16255446 | 0.73 | MRGPRX4 (0.51) | ARMRGPRX4TSHR | |
| SCHEMBL24074650 | 0.73 | AR (0.46) | ARMRGPRX4TSHR | |
| SCHEMBL17623897 | 0.71 | AR (0.53) | ARMRGPRX4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |