Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16609826 | 0.86 | AR (0.43) | ARPGRGPR3ACACBTRPA1 | |
| SCHEMBL28364202 | 0.80 | TRPV4 (0.48) | ARPGRGPR3ACACBTRPA1 | |
| SCHEMBL16955309 | 0.79 | GPR3 (0.41) | ARPGRGPR3ACACBTRPA1 | |
| SCHEMBL8148156 | 0.79 | AR (0.43) | ARPGRGPR3ACACBTRPA1 | |
| SCHEMBL967100 | 0.79 | AR (0.49) | ARPGRGPR3MRGPRX4TRPA1 | |
| SCHEMBL23831366 | 0.79 | SCN5A (0.41) | ARPGRGPR3ACACBTRPA1 | |
| SCHEMBL18621197 | 0.79 | AR (0.45) | ARMRGPRX4 | |
| SCHEMBL16961773 | 0.78 | ACACB (0.44) | ARPGRGPR3ACACBTRPA1 | |
| SCHEMBL17125203 | 0.78 | AR (0.49) | ARPGRGPR3ACACBTRPA1 | |
| SCHEMBL16955335 | 0.77 | ACACB (0.40) | ARPGRGPR3ACACBTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-2906542-B1 | SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME (US) | 2019-08-07 | — | — | EP | disclosed |
| US-9708270-B2 | Substituted spiropiperidinyl compounds useful as GPR120 agonists | MERCK SHARP & DOHME CORP. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20150274672-A1 | SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-10-01 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| WO-2014059232-A2 | SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2014-04-17 | — | — | WO | disclosed |
| EP-1178802-A4 | CYCLIC AMIDINES USEFUL AS NMDA NR2B ANTAGONISTS | MERCK & CO INC (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6376530-B1 | A N-METHYLASPARTIC ACID ANTAGONIST; NERVOUS SYSTEM DISORDERS, ANALGESICS | MERCK & CO., INC. | 2002-04-23 | — | — | US | disclosed |
| EP-1178802-A1 | CYCLIC AMIDINES USEFUL AS NMDA NR2B ANTAGONISTS | Merck & Co., Inc. (US) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000067755-A1 | CYCLIC AMIDINES USEFUL AS NMDA NR2B ANTAGONISTS | MERCK & CO., INC. (US) | 2000-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | OCIAD1, OCIAD2, SLCO4C1 | AR 1888/4885PGR 2323/4885GPR3 2866/4885 |
| US-20150274672-A1 | SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS | GPR119, GPR180, GPR88 | AR 184/4885PGR 650/4885GPR3 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.