Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359014 | 0.82 | MAOB (0.49) | ARKDM4EUSP2ALDH1A1MAOB | |
| SCHEMBL509379 | 0.80 | AR (0.50) | ARMRGPRX4TSHRPGRKDM4E | |
| SCHEMBL25680960 | 0.78 | AR (0.44) | ARMRGPRX4TSHRESRRASLC22A12 | |
| SCHEMBL1668579 | 0.78 | AR (0.61) | ARPGRKDM4EUSP2ALDH1A1 | |
| SCHEMBL1277499 | 0.77 | TRPV4 (0.50) | ARSLC22A12 | |
| SCHEMBL24074650 | 0.76 | AR (0.46) | ARMRGPRX4TSHRKDM4EALDH1A1 | |
| SCHEMBL16255446 | 0.76 | MRGPRX4 (0.51) | ARMRGPRX4TSHRKDM4EALDH1A1 | |
| SCHEMBL177356 | 0.74 | TDP1 (0.44) | ALDH1A1 | |
| SCHEMBL29804592 | 0.74 | TDP1 (0.44) | ALDH1A1 | |
| SCHEMBL17623897 | 0.74 | AR (0.53) | ARMRGPRX4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006134481-A1 | INHIBITORS OF 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1 | PFIZER INC. (US) | 2006-12-21 | — | — | WO | disclosed |